Background: For patients
with immunologically caused habitual abortion so far there
are only few therapies possible with limited success and
predominantly considerable side effects.
Objective: it was the aim of this
investigation to rate the benefit of systemic enzyme therapy
for pregnant women with habitual abortion in history by means
of the course of pregnancy and delivery including fetal outcome. Materials
and methods: 144 pregnant women with immunologically
caused abortion received a gestagen preparation and an enzyme
combination preparation and were observed up to delivery.
The current data of pregnancy, birth and child were collected
Results: 114 of 144 enzyme
treated pregnant women had an inconspicuous course of pregnancy
up to the. birth of 114 healthy children. Enzyme therapy
caused no unpleasant side effects.
Conclusions: For immunologically
caused habitual abortion enzyme therapy is an effective form
of immune therapy. The maternal immune system is stabilized
by the supplied enzymes whereby the full development of a
pregnancy is easier. The further clearing of the molecular
mechanisms of action is subject of current research projects.
Enzyme therapy can be recommended predominantly for women,
who had several abortions receiving the common forms of immune
therapy without success and therefore now are looking for
a therapeutical alternative. According to the previous experience
enzyme therapy is very successful for women with habitual
abortion with regard to completed pregnancies, and furthermore
well tolerated and also cost-effective.