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WAM Essentials, Inc.
Systemic Enzyme Therapy
... Allowing You to Live Your Passion!™ |
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Reduction of postoperative swelling. Objective
measurement of swelling of the upper ankle joint in treatment
with serrapeptase-- a prospective study
Author: Esch PM, Gerngross H, Fabian A.
Source: Fortschr Med. 1989 Feb 10;107(4):67-8, 71-2.
Department of Otorhinolaryngology, Mie University School
of Medicine, Japan. |
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We have evaluated the effect of serratiopeptidase (SER),
a proteolytic enzyme, on the elasticity and viscosity of
the nasal mucus in adult patients with chronic sinusitis.
SER was administered in a dose of 30 mg/day orally for 4
weeks. Nasal mucus was collected from the nasal cavities
of each patient before (week 0) and 4 weeks after the start
of the medication (week 4). The storage modulus (G') and
the dynamic viscosity (eta') of each specimen of nasal mucus
were determined by an oscillating sphere magnetic rheometer
at frequencies of 0.5, 1, 5, 10 and 20 Hz at a constant temperature
of 25 degrees C. The dynamic viscosity (eta') of the mucus
at week 4 was significantly lower than that at week 0 (at
frequencies of 5, 10 and 20 Hz). No significant differences
were observed in the storage modulus (G') between the mucus
at week 0 and week 4. SER reduced the viscosity but not the
elasticity of the nasal mucus. These findings are discussed
in relation to mucociliary clearance. |
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