OBJECTIVES: This study was planned to assess
the response of serratiopeptidase in patients with carpal
tunnel syndrome (CTS).
METHODS: Twenty patients with CTS
were evaluated clinically. After baseline electrophysiological
studies, these patients were given serratiopeptidase 10
mg twice daily with initial short course of nimesulide. Clinical
and electrophysiological reassessment was done after 6
RESULTS: Mean age was 43.9 years with male to female
ratio of 1:2.33. Sixty five percent cases showed significant
clinical improvement which was supported by significant
improvement in electrophysiological parameters. Recurrence
was reported in four cases. No significant side effect was
Serratiopeptidase therapy may proved to be a useful alternative
mode of conservative treatment. Larger study may be further
helpful to establish the role of serratiopeptidase in CTS.