WAM Essentials, Inc. logo

WAM Essentials, Inc.

Systemic Enzyme Therapy ... Allowing You to Live Your Passion!™

 

Lipoprotein Immune Complexes As Markers of Atherosclerosis

Orekhov A.N., Kalenich O.S., Tertov V.V., Novikov I.D.

USSR Cardiology Research Centre, Moscow, Russia.
Inter. Journal of  Tissue Reactions 1991, Vol. XIII, No. 5, pp. 233-236

323 KA

Divider

Summary

Recently we have demonstrated that cholesterol level in LDL-containing circulating immune complexes (CIC cholesterol) correlates with the presence of coronary atherosclerosis. In the present study we attempted to clarify whether CIC cholesterol level correlates with the severity of coronary atherosclerosis.

 The second task was to reveal the diagnostic value of CIC cholesterol in comparison with other lipid and lipoprotein parameters used as markers of dislipidaemia associated with atherosclerosis. The subjects were 107 patients with angiographically-documented coronary atherosclerosis and 66 patients with documented extracoronary atherosclerosis. Only CIC cholesterol and the apo B/apo A-1 ratio contributed strongly to the discrimination between patients with coronary atherosclerosis and those without stenoses. On the other hand, total cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, apo B, Lp(a) and apo A1 did not correlate with the presence and severity of coronary atherosclerosis. Subjects with stenosis of extracoronary arteries had significantly higher CIC levels than healthy donors. Sensitivity, specificity and accuracy of coronary atherosclerosis diagnosis were assessed for each parameter examined. It was revealed that CIC cholesterol is the most reliable marker of coronary atherosclerosis as compared to other chemical parameters. In addition, the CIC cholesterol level diagnoses extracoronary atherosclerosis with high accuracy.

Medical Disclaimer: We believe that the role of nutrition is important to good health, however, this web site is for informational purposes only and is not intended to be a substitute for professional medical advice. Our goal is to provide you, the customer, with the information necessary for you to make important nutritional and self-help decisions. We strongly suggest that you share any products you decide to use with your health care professional for optimal individual health benefits. Women who are planning on becoming pregnant or who are pregnant should not take any supplements without consulting their physician first. Information and statements on this website regarding dietary supplements have not been evaluated by the Food and Drug Administration, and are not intended to diagnose, treat, cure, mitigate or prevent any disease or health condition.

 
© Copyright 2004 WAM Essentials, Inc. All Rights Reserved.
None of the material contained herein may be reproduced without the prior written consent of WAM Essentials, Inc.